Refining cancer cell death and danger signals for the improvement of immunotherapy Ghent University
Interaction between dying cancer cells and the immune cells is crucial for eliciting productive
antitumor immunity that ultimately dictates the efficacy of cancer immunotherapy. Cell deathassociated
immunostimulatory signals (e.g. danger signals), clearance of cell corpses, tumor
antigen availability and antigen processing/presentation by antigen-presenting cells (APCs),
dictate the immunogenic and antigenic potential ...