Are mas-related gene receptors involved in irritable bowel syndrome? University of Antwerp
Mas-related gene receptors (Mrg) form a family of G-protein coupled receptors that has been implicated in nociception and mast cell activation. Previous work from our research group points towards a strong plasticity and role of the Mrg receptor family in intestinal inflammation. We now want to explore whether expressional changes of the Mrg receptor family are specific to inflammatory bowel disorders or also occur in irritable bowel syndrome ...