Publications
PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins. Flanders Institute for Biotechnology Vrije Universiteit Brussel
Exploring Curated Conformational Ensembles of Intrinsically Disordered Proteins in the Protein Ensemble Database. Flanders Institute for Biotechnology Vrije Universiteit Brussel
Intrinsically disordered proteins undergo and assist folding transitions in the proteome. Vrije Universiteit Brussel
pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins Vrije Universiteit Brussel
The goal of pE-DB (http://pedb.vib.be) is to serve as an openly accessible database for the deposition of structural ensembles of intrinsically disordered proteins (IDPs) and of denatured proteins based on nuclear magnetic resonance spectroscopy, small-angle X-ray scattering and other data measured in solution. Owing to the inherent flexibility of IDPs, solution techniques are particularly appropriate for characterizing their biophysical ...
Computational approaches for inferring the functions of intrinsically disordered proteins Vrije Universiteit Brussel
Intrinsically disordered proteins (IDPs) are ubiquitously involved in cellular processes and often implicated in human pathological conditions. The critical biological roles of these proteins, despite not adopting a well-defined fold, encouraged structural biologists to revisit their views on the protein structure-function paradigm. Unfortunately, investigating the characteristics and describing the structural behavior of IDPs is far from ...
Development of mass spectrometry approaches to characterize intrinsically disordered proteins α-synuclein University of Antwerp
MobiDB: intrinsically disordered proteins in 2021 Vrije Universiteit Brussel
The MobiDB database (URL: https://mobidb.org/) provides predictions and annotations for intrinsically disordered proteins. Here, we report recent developments implemented in MobiDB version 4, regarding the database format, with novel types of annotations and an improved update process. The new website includes a re-designed user interface, a more effective search engine and advanced API for programmatic access. The new database schema gives ...