Function and biogenesis of extracellular vesicle subsets in cancer Ghent University
Extracellular vesicles (EV) are polydisperse nanometer-sized membraneous structures containing
proteins, nucleic acids and metabolites. Their secretion is tightly regulated through Rab
GTPase/effector complexes, including Rab27b-melanophilin (Mlph) and viral Gag-like proteins,
including arrestin domain containing protein-1 (Arrdc1). We will use state-of-the-art density and size
based AF4 fractionation technology to ...