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Factors affecting preparers' and auditors' judgements about materiality and conciseness in integrated reporting University of Antwerp
Factors affecting preparers' and auditors' judgements about materiality and conciseness in integrated reporting University of Antwerp
A new approach to integrate toxicity grade and repeated treatment cycles in the analysis and reporting of phase I dose-finding trials KU Leuven
Safety assessment beyond the dose-limiting toxicity evaluation period provides relevant information to define the recommended phase II dose (RP2D) of a new treatment. We retrospectively analyzed three phase I trials to illustrate two indicators: per-cycle probability of graded toxicity and cumulative probability of severe toxicity over the treatment period.
Single-cell recording and stimulation with a 16k micro-nail electrode array integrated on a 0.18 μm CMOS chip KU Leuven
To cope with the growing needs in research towards the understanding of cellular function and network dynamics, advanced micro-electrode arrays (MEAs) based on integrated complementary metal oxide semiconductor (CMOS) circuits have been increasingly reported. Although such arrays contain a large number of sensors for recording and/or stimulation, the size of the electrodes on these chips are often larger than a typical mammalian cell. Therefore, ...
Fully integrated silicon probes for high-density recording of neural activity Flanders Institute for Biotechnology KU Leuven
A novel technology for natural gas conversion by means of integrated oxidative coupling and dry reforming of methane Ghent University
A Multichannel Integrated Circuit for Electrical Recording of Neural Activity, With Independent Channel Programmability KU Leuven
Since a few decades, micro-fabricated neural probes are being used, together with microelectronic interfaces, to get more insight in the activity of neuronal networks. The need for higher temporal and spatial recording resolutions imposes new challenges on the design of integrated neural interfaces with respect to power consumption, data handling and versatility. In this paper, we present an integrated acquisition system for in vitro and in vivo ...