Multiple sclerosis immunogenetics. KU Leuven
Research project multiple sclerosis immunogenetics: moving to multimodal single-cell resolution.
Research project multiple sclerosis immunogenetics: moving to multimodal single-cell resolution.
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system affecting 2.8 million people worldwide. It leads to disability in young adults. Thus far, no cure is available for MS and current therapies can come with severe adverse effects as they are based on the depletion of broad ranges of immune cells. Recently,
our group was closely involved in the identification of 236 MS risk variants through genome-wide ...
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that affects 2.5 million people worldwide and leads to important physical and cognitive disability with typical onset during young adulthood. Over the past years, the Laboratory for Neuroimmunology (KU Leuven) identified 233 MS genetic risk factors, which are shared with other autoimmune but not neurological disorders and implicate specific immune cells in the ...
Chronic arthritides are hardly studied in central Africa. Our recent studies in Rheumatoid arthritis in the DR Congo showed different demographic and phenotypic characheristics compared to a Caucasian population. Data in the field of Spondyloarthritis (SpA) are scarses. The current project aims to study the epidemiology, clinical diagnosis including immunogenetic phenotype and management of SpA in Kinshasa, DR Congo. It will be based on four ...
Multiple sclerosis (MS) is one of the most common neurological disorders in young adults, affecting around 10,000 people in Belgium and leading to important physical as well as cognitive disability. MS is characterized by three hallmarks: inflammation, demyelination and axonal loss. More than 200 genetic risk factors for MS have been identified. These genetic risk factors indicate a primary role for the immune system in MS, and have ...