Projects
Bipotential progenitor cells to treat cardiac and skeletal muscle degeneration in a large animal model of Duchenne Muscular Dystrophy. KU Leuven
Duchenne Muscular Dystrophy (DMD) causes untreatable and progressive degeneration of cardiac and skeletal muscles. Cell therapies are emerging as curative approach to functionally regenerate damaged muscles, yet strategies to equally target both muscle types are still missing. Induced pluripotent stem cells (iPSCs) are raising new expectations in the field, given the unprecedented possibility of patient-matched cells virtually differentiating ...
Bone tissue engineering: Properties of periosteal cells vary according to their origin KU Leuven
Bone grafts are commonly used in orthopedics, traumatology, and oral and maxillofacial surgery for treating bone defects caused by trauma, oncologic resection, congenital malformations, and prosthetic treatments. There are still limitations and complications associated with the current standard of using autologous bone tissue as grafts. These include donor site morbidity, inadequate quantities of available donor tissue, ultimate poor tissue ...