Non-Amyloid Pathological Brain Aging in Late Life Depression KU Leuven
Understanding the aetiology of medial temporal lobe (MTL) pathology in severe late-life depression (LLD) is crucial for improving diagnostic specificity with respect to dementia and for optimising treatment. Given the role of tau in neurodegenerative diseases and our recent finding that hippocampal atrophy in LLD is not related to brain amyloid, we will study non-amyloid pathological brain aging in LLD using PET-MRI neuroimaging. We will ...