Projects
Is arterial stiffness an overlooked marker in cardio-oncology? University of Antwerp
Assessment of Mechanical Dyssynchrony as Selection Criterion for CRT Treatment KU Leuven
Cardiac resynchronization therapy is an accepted treatment for patients with heart failure and conduction delays, where the contraction of the left ventricular chamber is re-synchronized by means of a dedicated pacemaker device with several electrodes. Current guideline criteria for selecting patients, however, result in a non-responder rate of approximately 35%. Some studies suggest that such non-responders are even at higher risk because of ...
Connecting digital mobility assessment to clinical outcomes for regulatory and clinical endorsement KU Leuven
Optimal treatment of the impaired mobility resulting from ageing and chronic disease is one of the 21st century's greatest challenges facing patients, society, governments, healthcare services, and science. New interventions are a key focus. However, to accelerate their development, we need better ways to detect and measure mobility loss. Digital technology, including body worn sensors, has the potential to revolutionise mobility assessment. ...
CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease (OZR EU Bonus). Vrije Universiteit Brussel
CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease Vrije Universiteit Brussel
WHO estimates 17.7 million people die each year from cardiovascular disease (CVD), an estimated 31% of all deaths worldwide. While progress with conventional treatments is making incremental gains, there remains a need to develop innovative therapeutic approaches. Gene therapy has gained significant momentum, mainly for treatment of rare monogenetic diseases. Marketing authorization for gene therapy products has not impacted ...
Value-based healthcare of state-of-the-art care pathways for adult spinal deformity in University Hospitals Leuven Vlerick Business School
Identificatie van kleine moleculaire ErbB4 agonisten ter behandeling van cardiovasculaire ziekten. University of Antwerp
Value-based healthcare of state-of-the-art care pathways for adult spinal deformity in University Hospitals Leuven. KU Leuven
Healthcare providers, working with limited healthcare budgets, attempt to achieve better clinical outcomes at lower costs of care and thus, to improve the so-called “value in healthcare”. Improving value certainly benefits diseases with a high financial and clinical burden on society, such as Adult Spinal Deformity (ASD), a chronic disease affecting the ageing population. Especially in these chronic diseases, with lifelong outcome (and cost) ...
Neuropeptidergic regulation of food leaving and nictation behaviour in Caenorhabditis elegans KU Leuven
The most recent human pandemic is not caused by a virus or bacteria, but by man’s feeding habits. Our increased caloric intake coupled to a decline in physical activity resulted in an exponential increase of overweight and obese people in the recent decades. Obesity is a major risk factor that increases the chances on heart failure, diabetes, cancer and a lot of other life-threatening illnesses. In order to counter all the health risks that ...