Building a Precision Medicine Pipeline for Antibody-Mediated and Antibody-Independent Phenotypes of Microvascular Rejection After Kidney Transplantation KU Leuven
Immunosuppressive regimens for prevention and treatment of rejection have been established over the past 50 years, but focused on T-cell activation and proliferation. Long-term outcome after renal transplantation is impaired, which is attributed in large part to rejection caused by donor-specific HLA antibodies. Although it is becoming clear that antibody-mediated rejection is the prime cause of late renal allograft failure, preventative ...