Organisations
Laboratory for Cancer Genomics KU Leuven
Cancers develop due to the accumulation of somatic mutations in the genome. The Laboratory for Cancer Genomics studies these mutations and leverages them to elucidate the evolutionary history of cancers. In this endeavour, we make use of new sequencing technologies and new bioinformatics analysis approaches.
Laboratory of Integrative Cancer Genomics (VIB-KUÂ Leuven) KU Leuven
The Lab for Integrative cancer Genomics develops computational approaches to comprehensively chart genomic and epigenetic variation using sequencing data and elucidate their contributions to somatic evolution, tumour heterogeneity, and treatment resistance.
Laboratory of Reproductive Genomics KU Leuven
Our group focuses on:
(1) The development of wet-lab and computational methods for single-cell multi-omics analyses –including genome, epigenome and transcriptome analyses of single cells– using microarray and next-generation sequencing technologies. We furthermore automate these methods using customised liquid handling robotics and microfluidics.
(2) The application of these methods to study the nature, rate and mechanisms of ...
Applied Genetics and Breeding Research Institute for Agriculture, Fisheries and Food
In this research area, we survey the genetic diversity, habitat and evolution over time of plant populations. Relationships between and among genetic sources are applied to breeding. This breeding research includes development and use of molecular markers, embryo rescue, polyploidization and protoplast fusion. We make (interspecific) crosses with improved disease resistance, better use of nutrients, drought resistance, and more.
Cell Genetics Vrije Universiteit Brussel
The laboratory for Cell Genetics (Cytogenetics) studies variation in genotype and phenotype, cell division pathways, cell death and genetic changes relevant for the increase of cancer in human. Genotoxicity tests assess the induction of DNA damage, gene mutations, structural and numerical chromosome aberrations. Their predictivity for cancer induction is supported by international studies relating mutations and activation of cancer related ...
Centre for Medical Genetics Vrije Universiteit Brussel
Topic A : Identification of new mutations in hereditary diseases (W. Lissens, I. Liebaers), more in particular: - cystic fibrosis - iduronate sulphate deficiency - Beta-glucuronidase deficiency - anti thrombosis III deficiency Topic B : Preimplantation genetics/expression (Liebaers I, Lissens W.) - expression Beta-hexosaminidase in mouse and human embryo's - preimplantation diagnosis in couples at risk for cysticfibrosis (F508) or couples at ...
Centre of Microbial and Plant Genetics KU Leuven
Research topics of this unit are:
• Bacteria-plant interactions
• Symbiosis between Rhizobium etli and Phaseolus vulgaris
• Symbiotic nitrogen fixation
• Quorum sensing and biofilm formation in Rhizobium
• Bacterial physiology: the stringent response in Rhizobium
• Type III protein secretion in Rhizobium
• Calcium-binding proteins in bacteria
• Mechanisms of antibiotic resistance and tolerance in ...
Clinical Genetics KU Leuven
The Divsion for Clinical Genetics has two research fields:
- The Identification of new malformation syndromes (dysmorphology)
- The identification of genes involved in the pathogenesis of congenital malformations, mental retardation (mainly X-linked forms) and developmental disabilities in general (mainly autism)