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Conservation genetics of an endemic from the Mediterranean Basin: high genetic differentiation but no genetic diversity loss from the last populations of the Sicilian Grape Hyacinth Leopoldia gussonei Research Institute for Agriculture, Fisheries and Food Ghent University KU Leuven
The Mediterranean Basin is a biodiversity hotspot, housing[11.000 narrowly endemic plant species, many of which are declining due to mass tourism and
agricultural intensification. To investigate the genetic resource impacts of ongoing habitat loss and degradation, we characterized the genetic variation in the last known populations of Leopoldia gussonei, a self-compatible endangered Sicilian Grape Hyacinth numbering less than 3,000 ...
Veterinarians’ competence in applying basic genetic principles and daily implementation of clinical genetics : a study in a university environment Ghent University
Veterinarian competency in genetics is vital for a meaningful application of the rapidly growing number of genetic tests available for animals. We evaluated the use of genetic tests in the daily veterinary practice and the competency of university-employed veterinarians in applying basic principles of genetics in a clinical setting through an electronic survey with 14 cases and 7 statements on genetics. Ninety-one non-geneticist veterinarians ...
High-dimensional Bayesian network inference from systems genetics data using genetic node ordering Ghent University
Studying the impact of genetic variation on gene regulatory networks is essential to understand the biological mechanisms by which genetic variation causes variation in phenotypes. Bayesian networks provide an elegant statistical approach for multi-trait genetic mapping and modelling causal trait relationships. However, inferring Bayesian gene networks from high-dimensional genetics and genomics data is challenging, because the number of ...
Consensus paper of the WFSBP Task Force on Genetics: Genetics, epigenetics and gene expression markers of major depressive disorder and antidepressant response KU Leuven
Major depressive disorder (MDD) is a heritable disease with a heavy personal and socio-economic burden. Antidepressants of different classes are prescribed to treat MDD, but reliable and reproducible markers of efficacy are not available for clinical use. Further complicating treatment, the diagnosis of MDD is not guided by objective criteria, resulting in the risk of under- or overtreatment. A number of markers of MDD and antidepressant ...
Public views on genetics and genetic testing : a survey of the general public in Belgium Ghent University KU Leuven
Mycobacterium tuberculosis complex genetic diversity: mining the fourth international spoligotyping database (SpolDB4) for classification, population genetics and epidemiology Institute of Tropical Medicine
Genetic Counselling in Belgium: the Centre for Human Genetics at the University of Leuven, 1960-1990 KU Leuven
© Springer International Publishing AG 2017. All rights reserved. This chapter traces the history of the Center for Human Genetics (CHG)- the first centre of this kind in Belgium-at the University of Leuven from the 1960s to the 1990s. In 1960, a laboratory for diagnostic chromosomal research was set up by the physician and geneticist Herman Van den Berghe. In 1966, this laboratory was turned into the Center for Human Genetics (CHG), which ...
Human Genetics Society of Australasia Position Statement: Predictive and Presymptomatic Genetic Testing in Adults and Children. KU Leuven
This Position Statement provides guidelines for health professionals who work with individuals and families seeking predictive genetic testing and laboratory staff conducting the tests. It presents the major practical, psychosocial and ethical considerations associated with presymptomatic and predictive genetic testing in adults who have the capacity to make a decision, children and young people who lack capacity, and adults living with reduced ...