Genetics and physiology of bimodal protein targeting in yeasts. Studies on the basic mechanisms and possible therapeutic developments. KU Leuven
Cytochrome P450s (CYPs) are proteins that play an enormous role in our life. They synthesize many of our endogenous chemicals, they inactivate most of the drugs we assume (i.e., that’s the reason why the pain killers we take lose potency after a few hours), and also detoxify dangerous pesticides we come frequently in contact with, making our bodies capable of flushing them away CYPs reside mostly in an intracellular organelle called ...