Publications
Insufficiently defined genetic background confounds phenotypes in transgenic studies as exemplified by malaria infection in Tlr9 knockout mice Vrije Universiteit Brussel
Genetic association studies of obesity in Africa Vrije Universiteit Brussel
Obesity is increasing in Africa, but the underlying genetic background largely remains unknown. We assessed existing evidence on genetic determinants of obesity among populations within Africa. MEDLINE and EMBASE were searched and the bibliographies of retrieved articles were examined. Included studies had to report on the association of a genetic marker with obesity indices and the presence/occurrence of obesity/obesity trait. Data were ...
Long-term population studies uncover the genome structure and genetic basis of xenobiotic and host plant adaptation in the herbivore Tetranychus urticae Ghent University
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies University of Antwerp
Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies KU Leuven
Expanding GNAS-related pathology by genetic and epigenetic studies KU Leuven
TheGNAS cluster, located on chromosome20q13 gives rise to several transcripts, antisensetranscripts andnoncoding RNAs, including transcription of the gene for the stimulatory G-proteinalpha subunit (Gsα), which interacts with adenylyl cyclase to generate cAMP. It comprisesfour alternative first exons and promoters that splice onto exon 2 of theclassical GNAS gene, and that are alllocated in three differentially methylated ...