Gamma-glutamyl transpeptidase as a major virulence factor of Helicobacter suis: mechanisms leading to epithelial cell necrosis and immune modulation Ghent University
Helicobacter suis is the most prevalent non-Helicobacter pylori Helicobacter species in humans suffering from gastric disease. We aim to unravel the mechanisms used by this bacterium and its gamma-glutamyl transpeptidase to cause gastric epithelial cell death on one hand and to modulate the host immune response on the other hand.