Projects
Metakey framework to perform metabolite profiling and fingerprinting Ghent University
Metakey framework to perform metabolite profiling and fingerprinting
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Metabolic fingerprinting towards diagnosis and prognosis of cow's milk allergy in children. Ghent University
Given the emerging evidence for the involvement of the gut microbiome in the onset of food allergy
and its resolution, this project will rely on our metabolomics platform and microbial analysis of CMA patients' biofluids, for identifying prognostic biomarkers. Specific bacterial groups involved in the biomarker formation, will be manipulated or administered to mice to aid in biomarker qualification.
Microbial community fingerprinting as a biological indicator for pathogen outgrowth in engineered aquatic systems Ghent University
This project will combine flow cytometry with advanced metagenomics to observe and quantify the response of a receiving microbial community to the invasion of Legionella sp.. Besides identifying characteristic patterns, particular attention will be given towards designing biological metrices which can be applied to predict potential pathogen invasions. The approach will then be validated with a laboratory and full-scale cooling water ...
Metabolic fingerprinting of the human gut phenotype in health and disease Ghent University
The main objective of this innovative research is to characterize ‘metabolic phenotypes’, by means of a high resolution full scan Orbitrap mass spectrometer, which will analyse feces, intact biopsies or exfoliated colonocytes. At a later stage of the research these metabolomic fingerprints may serve as a specific statistically founded prediagnostic screening tool for different types of gastrointestinal disorders (inflammatory bowel disease ...
Providing scientific assistance in the sediment Fingerprinting of the Waterbouwkundig Laboratorium. University of Antwerp
Modular Confocal Raman Microscope Ghent University
The envisioned equipment comprises of a modular confocal Raman microscope for bio-imaging and identification of (bio-)molecules (molecular fingerprinting). The setup includes a microscope body with positioning stage, Nd-YAG laser, detectors and spectrometers as well as a sensitive Peltier-cooled CCD camera and allows for visualizing chemical properties with diffraction limited resolution.