Uncaging the potential of photopharmacology for the treatment of epilepsy Ghent University
Various brain disorders, such as epilepsy, are caused by sporadic abnormal activity of neurons in specific parts of the brain. These disorders are treated with drugs that influence the whole brain and body and therefore cause off-target side effects. Ideally drugs would act only WHEN and WHERE needed. This is possible with photopharmacology, where inactive prodrugs are activated by light. This project aims to develop original photocages, ...