Novel approaches to prevent transmission of mitochondrial diseases: filling in the safety gaps towards clinical application Ghent University
Nuclear transfer (NT) is a newly proposed procedure in assisted reproductive technology, involving the transfer of the nuclear genome from a patient’s diseased oocyte or zygote to a donor’s healthy, enucleated counterpart. This approach has been suggested for preventing the transmission of mitochondrial DNA (mtDNA) diseases, which can lead to incurable and life-threatening conditions.
The current first line treatment ...