Projects
SOCMA (Singlet Oxygen-based photoelectrochemical bioplatform for cancer mutations): from clinical current technologies with limitations towards innovative tools for early diagnosis and monitoring (SOCMA). University of Antwerp
Blood based biomarkers for early diagnosis and prognosis of amyotrophic lateral sclerosis. KU Leuven
Amyotrophic lateral sclerosis (ALS) is a rare progressive neurodegenerative disease characterized by the degeneration of upper motor neurons and lower motor neurons. The first symptoms associated with the disease are muscle weakness, muscle atrophy and fasciculations. To date, ALS is a fatal disease as no cure is available. The diagnosis of ALS is based on clinical symptoms, electrophysiological examinations, progression of the symptoms and ...
Multimodal imaging of retinal manifestations of Alzheimer’s disease for early diagnosis and clinical research KU Leuven
Although Alzheimer’s disease (AD) is the number one dementia cause, the currently available diagnostic techniques (brain imaging and cerebrospinal fluid sampling) do not allow preclinical diagnosis or screening due to their high cost, limited resolution and invasiveness. These limitations result in delayed treatment onset and unsuccessful drug development. The retina offers a unique opportunity to overcome these limitations since the ...
Multimodal imagiNg of rEtinal ManifestatiOns of Alzheimer’s diseaSe for earlY diagNosis and clinical rEsearch. KU Leuven
ProFiLE:Standardized multi-parameter flow cytometry for early diagnosis, risk assessment and optimized treatment in primary immunodeficiency KU Leuven
Primary Immune Deficiency diseases (PIDs) comprise a heterogeneous group of life-threatening genetic disorders of the innate and adaptive immune system. To date, more than 400 different PID subtypes with more than 300 PID causing genes have been unraveled. However, there is still a lot of underdiagnosis due to the clinical heterogeneity in disease presentation even among patients with the same genetic pathogenic variant. Further complicating ...
PremAtuRe nEwborn motor and cogNitive impairmenTs: Early diagnosis KU Leuven
Prematurity exponentially increases the risk for an altered neurodevelopmental outcomes in childhood and adolescence. Many survivors children, face a lifetime of disability. Despite the advances in neonatal care have greatly improved survival of preterm born infants even at extremely low gestational ages we are now at a period of steadiness where no further improvement in long-term neurodevelopmental outcome is seen. The impact of these ...
Supporting early diagnosis for diastolic heart failure KU Leuven
The HERCULes project team have created a new solution that uses high frame rate imaging of the heart to assess myocardial stiffness as a diagnostic biomarker of diastolic function. This new diagnostic tool promises to support the early diagnosis of heart failure with preserved ejection fraction (HFpEF).
Discovery of metabolite biomarkers for early diagnosis and prognosis of cow's milk allergy in children Ghent University
Cow’s milk allergy (CMA) is one of the most prevalent and first food allergies to occur in early
childhood. Diagnosis of CMA currently relies on challenge-based tests, which have to be repeated
on a yearly basis to assess possible spontaneous resolution. These tests inherently result in allergic
reactions in patients. As metabolites represent the total contribution of genomic, transcriptomic
and proteomic activities, ...