Decoding tumor antigens: dendritic cell maturation within the tumor environment Ghent University
How tumor antigens are being perceived by dendritic cells (DCs) determines whether the tumor will
be tolerated or rejected by our immune system. Over the past years, immune checkpoint blockade
therapy (ICB) has revolutionized cancer therapy by removing so-called checkpoints that prevent our
immune system from properly functioning against the tumor cells. Although ICB showed high
potential in some patients, many ...