Zebrafish as a novel organism model to study immunogenic cell death-related mechanisms KU Leuven
Immunogenic cell death (ICD) is a cell death modality induced by specific clinically used anticancer therapeutics, which is able to stimulate anti-tumor immunity. It can result in an anticancer vaccination effect during treatment. All knowledge existing so far on ICD and immunosurveillance has been generated in mice models. However, the use of mice is accompanied with prolonged times for the establishment/growth of neoplastic lesions and ...