Projects
Metabolic aspects of organ failure in critical illness: role of blood glucose levels and variation of nutritional intake. KU Leuven
Mitochondrial abnormalities in critical illness: role in organ failure and mortality, underlying mechanisms and therapeutic perspectives. KU Leuven
Mitochondrial abnormalities in critical illness: role in organ failure and mortality, underlying mechanisms and therapeutic perspectives. KU Leuven
Impact of metabolic interventions on atrial fibrillation during critical illness: focus on tight glucose control with insulin and early macronutrient availability. KU Leuven
Atrial fibrillation (AF) is a very common and clinically relevant problem during critical illness. Current treatment strategies are symptomatic and don’t primarily address underlying etiology. Inflammation and oxidative stress are well recognized triggers for AF induction, while changes in atrial metabolism are increasingly recognized in its pathogenesis. Tight glucose control with insulin has been shown to reduce both inflammation and ...
Regulation of the thyroid axis during critical illness: a study of the peripheral changes during the low T3 syndrome - exploring safe reactivation strategies. KU Leuven
New knowledge discovery regarding causes and consequences of paediatric critical illnesses via complex analyses of DNA methylation KU Leuven
Intensive care is a data rich discipline with very large databases of raw data routinely registered for individual patients from a myriad of information sources. These comprise not only one-time demographic and admission information but also time series of diverse physiological signals, medications and treatments, laboratory analysis and with the advent of "omics", also genetic and epigenetic information. Patients are also routinely ...
Improving the clinical management and facility-based surveillance of febrile illness in rural Guinea: a multidisciplinary approach Institute of Tropical Medicine
SRP-Onderzoekszwaartepunt: Addressing the challenges around serious illness, palliative care and the end of life: public health, health services and clinical innovations Vrije Universiteit Brussel
Improving clinical management of mental illness using technology assisted Experience Sampling Methods. KU Leuven
As a research tool, experience sampling method (ESM) has enabled researchers to gain novel insights into the mechanisms of mental illnesses. With new developments in digital technologies to support health care delivery and management, application of ESM to clinical settings has become more feasible. By providing clinicians and patients with detailed information about how mental states of the patient fluctuate in daily-life, ESM can aid the ...