Role of cell adhesion-mediated signaling in craniofacial malformations: an integrated molecular and morphological study Ghent University
The research consortium analyzes how classical cadherins and delta-protocadherins, as well as their associated intracellular signaling pathways, are involved in correct development of complex craniofacial structures. Xenopus models will be used to screen for the most relevant molecules; those will be analyzed functionally in both Xenopus and zebrafish; the most interesting molecules will eventually be analyzed in mouse models.
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