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Content Analysis of Informed Consent for Whole Genome Sequencing Offered by Direct-to-Consumer Genetic Testing Companies Hasselt University KU Leuven
Whole exome sequencing (WES) and whole genome sequencing (WGS) have become increasingly available in the research and clinical settings and are now also being offered by direct-to-consumer (DTC) genetic testing (GT) companies. This offer can be perceived as amplifying the already identified concerns regarding adequacy of informed consent (IC) for both WES/WGS and the DTC GT context. We performed a qualitative content analysis of Websites of four ...
How do consent forms for diagnostic high-throughput sequencing address unsolicited and secondary findings? A content analysis KU Leuven
Whole exome and whole genome sequencing are increasingly being offered to patients in the clinical setting. Yet, the question of whether, and to what extent, unsolicited findings (UF) and/or secondary findings (SF) should be returned to patients remains open and little is known about how diagnostic consent forms address this issue. We systematically identified consent forms for diagnostic genomic sequencing online and used inductive content ...
Informed consent in the context of pharmacogenomic research: ethical considerations KU Leuven
Although the scientific research surrounding pharmacogenomics (PGx) has been relatively plentiful, the ethical research concerning this discipline has developed rather conservatively. Following investigation of the ethical, legal and social issues (ELSI) of PGx research, as well as consulting with key stakeholders, we identified six outstanding ethical issues raised by the informed consent process in PGx research: (1) scope of consent; (2) ...
Context based selection of user generated content Ghent University
Nowadays, there is a lot of interest in context- aware services, especially those services taking user interests into account. An important example is the automated filtering of the overwhelming amount of information available on the Internet. There is a clear need for services taking the context of the user into account to provide him with the information he needs in a particular situation. In this paper such a personalized content service is ...
Context aware recommendations for user-generated content on a social network site Ghent University
The enormous offer of video content on the internet and its continuous growth make the selection process increasingly difficult for end-users. This overabundance of audio-visual material can be handled by a recommendation system that observes user preferences and assists people with finding interesting content. However, present-day recommendation systems focus on the metadata or the previous consumption behaviour to select the content but do not ...
Pedagogical content knowledge: A systematic review of the way in which the concept has pervaded mathematics educational research KU Leuven
Pedagogical content knowledge (PCK) was introduced by Shulman in 1986 and refers to the knowledge teachers use to translate particular subject matter to students, taking into account possible (mis)conceptions. PCK was and still is very influential in research on teaching and teacher education, mainly within the natural sciences. The present study aims at a systematic review of the way PCK was conceptualized and (empirically) studied in ...