Projects
Biomedical Engineering for Improved Diagnosis and Patient-Tailored Treatment of Aortic Aneurysms (AA) and Dissections Ghent University
- accurate assessment of risk of rupture of AA and dissected aorta via integrated, patient-specific analysis of biological (molecular imaging) and biomechanical actors- simulation-based pre-operative treatment planning- fundamental research on the (molecular) biological and biomechanical key players and their interaction in the development of AA/dissection- improved patient-specific design of prostheses and search for new and/or modified ...
Exoskeletons and active orthoses: Robotic systems for augmented human motion. KU Leuven
How to switch on a complex brain: single-cell technologies to connect emergent nervous system activity with neural cell specification. KU Leuven
Contributions of history dependent muscle action to stability and efficiency of whole body human movements. KU Leuven
Contributions of history dependent muscle action to stability and efficiency of whole body human movements KU Leuven
Computer models have become an important tool to understand causal mechanisms underlying human movement. Simulating realistic musculoskeletal dynamics is critical to understanding neural control of muscle activity and motor performance. State-of-the-art simulations of motion are based on phenomenological muscle-tendon models that do not take into account the history dependence of muscle action. However, force enhancement and depression ...
Modeling non-invasive arterial tissue characterization using ultrsound Ghent University
In this PhD-project, we aim to investigate the potential of ultrasound to quantify the mechanical properties of healthy and pathological arterial tissue based on computational models. First, we will acquire more insight into the interaction of acoustic waves with the tissue at microstructural level. Secondly, clinically applicable ultrasound modalities for arterial tissue characterization will be simulated and validated.
The influence of the acceleration profile on the walk-to-run transition Ghent University
Research on gait transitions are characterized by different accelerations. Up till now the influence of acceleration on the realization of the walk-to-run transition is unknown. The second law of Newton (F=ma) learns us that different accelerations lead to different force profiles. The latter could lead to differences in the actual realization of transition and by consequence affect the determinants of transition.
Sabbatical Ilse Jonkers: Multi-scale insights in the role of mechanical loading in cartilage homeostasis, repair and disease as basis for regenerative rehabilitation and excercise regimes in osteoarthritis KU Leuven
I wish to strengthen my research line in multi-scale cartilage mechanobiology by deepening existing international collaborations or starting up new collaborations and embedding them further within my research line on cartilage mechanobiology in Leuven – in preparation for an ERC advanced grant (submission 2024). To this end, I would like to propose a 3-part approach: - Stay in AO Foundation (Davos, Switzerland) with which I already cooperate. ...