Projects
Computational modeling of short- and long-term affect dynamics KU Leuven
A Computational Framework for Prioritization of Disease-causing Mutations KU Leuven
Computational aspects of uncertainty propagation in large and multiscale systems. KU Leuven
WaterREACT (Water Reuse and Exchange Advanced Computational Tool): A decision support tool for planning circular water use in industry. University of Antwerp
Bootstrapping operations in language acquisition: a computational psycholinguistic approach. University of Antwerp
Computational study of protein-ligand interactions: Case study of SERCA and biofilm involved proteins KU Leuven
The goal of this PhD project was to use computational methods such as molecular docking and molecular dynamics (MD) simulations to gain a detailed insight into the structural basis of particular protein-ligand complexes. Here
these methods were applied on two case studies: a family of Ca2+ transporters called Sarco-/Endoplasmic Reticulum Ca2+-ATPase (SERCA), implicated in heart failure, and biofilms, an aggregate of micro-organisms ...
SoundsGood! – An integrated platform for studying ultrasonic vocalizations in rodent models for brain disorders. KU Leuven
Modeling human mental disorders in rodents is an extremely daunting challenge, given the subjective nature of many symptoms, the lack of relevant biomarkers and objective diagnostic tools, together with the early state of the pertinent neurobiology and genetics. The identification of new therapeutic targets is at a near standstill. We are convinced that a deeper understanding of the natural rodent behavior repertoire and its relevance for ...