Optimal blocked and split-plot designs ensuring precise pure-error estimation of the variance components University of Antwerp KU Leuven
Textbooks on response surface methodology generally stress the importance of lack-of-fit tests and estimation of pure error. For lack-of-fit tests to be possible and other inference to be unbiased, experiments should allow for pure-error estimation. Therefore, they should involve replicated treatments. While most textbooks focus on lack-of-fit testing in the context of completely randomized designs, many response surface experiments are not ...