Genetic diversity of rotaviruses and co-segregation of rotavirus gene segments in reassortants. KU Leuven
Rotaviruses possess a genome containing 11 segments of double stranded RNA. Reassortment among rotaviruses infecting the same cell, resulting in reassortant rotaviruses, possessing gene segments from both parental strains, is a frequently occurring phenomenon in nature. This process, involving all 11 genome segments, leads to a great genetic diversity. In this project we will introduce a new technique in our laboratory, to sequence complete ...