Deciphering the molecular mechanism that account for intestinal barrier dysfunction in cirrhosis KU Leuven
Cirrhosis is the end result of chronic liver diseases and its pathophysiology is paired with a progressive breach of the intestinal barrier. In my research proposal, I shall address the fundamental question on how the intestinal barrier fails in cirrhosis. In the lab wel apply single-cell RNAsequencing to survey the transcriptional landscape of epithelial and immune cells from control and cirrhosis patients to map cellular and molecular ...