Expert laboratory: Chlamydiaceae diagnostics and vaccine development Ghent University
Researh towards Chlamydia diagnosis and vaccine development
Researh towards Chlamydia diagnosis and vaccine development
One of the main obstacles in applying engineering approaches to biological processes remains dealing with inter- and intra-individual differences. Therefore, it is highly challenging to accurately monitor their individual state (cfr. personalised medicine). The general objective of this PhD is to develop a framework for individualised model-based monitoring for biological processes, as inspired by control engineering concepts. The presented ...
The aim of this project is to find an explanation for the variability and differences in oral bioavailability of drugs in veterinary medicine, taking into account differences in drugs dissolution, gastro-intestinal (GI) transit time, GI fluid volume, GI pH, GI permeability and food effects. Therefore, the laboratories of Pharmacology & Toxicology and Pharmaceutical Technology recently started joined research with a PhD student to study ...
Fibrosis drives disease in many cardiovascular and dermatological conditions. Myhre syndrome
(MYHRS) is a Mendelian profibrotic disorder with progressive multisystem involvement, including
cardiovascular defects (aortic stenosis), a stiff and thickened skin, and musculoskeletal involvement.
Affected individuals may show intellectual disability and autism. MYHRS is caused by recurrent
pathogenic variants (PV) in SMAD4 ...
This project explores the motivations behind the alternation between the Dative Construction (e.g. Sie sendet dir einen Brief) and the Prepositional Construction (e.g. Er sendet den Aufsatz an den Herausgeber) with ditransitive TRANSFERverbs (geben, senden, schicken etc.) in the history of ‘New High German’ (ca. 1650 until present). The focus is on (i) the changing frequencies and forms of the alternation and on (ii) the role of different ...
There has been tremendous progress in the field since the early 21st century
of the conflict archeology of the First World War (Van Hollebeeke,
Stichelbaut et al. 2014) various initiatives of the Flemish Government (de Meyer
and Demeyere 2006, Dewilde 2006, Dewilde, de Meyer et al. 2007, Dewilde,
Verboven et al. 2016), a growing academic interest in ...