Screening platform for therapies for peripheral neuropathies (SCREEN4PN) in induced pluripotent stem cell derived 2D and 3D models (development phase 2). University of Antwerp
SCREEN4PN is a validation platform for therapeutics and biomarkers for Charcot-Marie-Tooth (CMT) neuropathy in induced pluripotent stem cell (iPSC) derived 2D and 3D models. CMT is a progressive peripheral neuropathy resulting in muscle weakness and atrophy in children and adults. The development of efficient therapies is complicated by the clinical and genetic heterogeneity of these incurable hereditary neuropathies. Most CMT therapeutic ...