Remote allograft rejection diagnosis by epigenetic changes in circulating cell-free DNA in kidney transplanted patients. KU Leuven
Kidney transplantation (KT) is the preferred treatment for patients with end-stage kidney disease, but long-term graft survival is still compromised by a rate of alloimmune rejection of about 15%. At present, there are no available non-invasive biomarkers that can accurately predict or detect graft rejection. In this PhD project we will explore cell-free DNA (cfDNA) as a novel, non-invasive, and accurate biomarker for monitoring KT ...