Role and molecular mechanisms of cell-cell adhesion signaling to the cytoskeleton in skeletal development. KU Leuven
Cell migration is a crucial process throughout development and postnatal life, choreographing embryonic morphogenesis, regulating homeostatic and repair processes in the adult, but also contributing to numerous pathologies including cancer. The interactions between cadherins, catenins and the actin cytoskeletal network at cell junctions are known to play essential roles in cell adhesion and migration, but their in vivo significance and ...