Projects
NOn-VIral gene modified STEM cell therapy Ghent University
Despite the increasing awareness that cell and gene-therapy approaches have tremendous biomedical potential, their broad clinical application has been challenging due to prolonged and expensive production times and the emergence of severe immune- and gene-delivery dependent side effects. In this proposal, we aim to establish a stream-lined and high-throughput protocol for iPSC-based cell therapy by combining a novel technological platform for ...
INnovative Training in Myeloid Regulatory Cell Therapy (INsTRuCT). University of Antwerp
Exploring the market potential of photoporation as the next generation of intracellular delivery technology for the R&D and cell therapy markets Ghent University
Delivering macromolecular compounds into living cells in vitro or ex vivo is a common requirement for both fundamental biological research as well as biomedical applications. Examples include the intracellular delivery of gene editing molecules to unravel molecular pathways or to create engineered therapeutic cells. Photoporation, which combines laser irradiation with light-sensitive nanomaterials, is an upcoming physical intracellular ...
New approaches for the targeted therapy of Non-Small Cell Lung Cancer. KU Leuven
A LAB-ON-A-CHIP DEVICE FOR PURE CIRCULATING TUMOR CELL ISOLATION FROM WHOLE BLOOD FOR CANCER THERAPY (pureCTC) Vrije Universiteit Brussel
CTCs are rare cells that originate from tumors, and which travel in the human circulatory system to eventually spread the disease to other organs. Consequently, analysis of CTCs is crucial for ...