Projects
CardioReGenix: Development of Next-Generation Gene Therapies for Cardiovascular Disease Vrije Universiteit Brussel
WHO estimates 17.7 million people die each year from cardiovascular disease (CVD), an estimated 31% of all deaths worldwide. While progress with conventional treatments is making incremental gains, there remains a need to develop innovative therapeutic approaches. Gene therapy has gained significant momentum, mainly for treatment of rare monogenetic diseases. Marketing authorization for gene therapy products has not impacted ...
Determinants and effects of mergers and acquisitions on innovation: Evidence from drug projects in the pharmaceutical industry KU Leuven
Innovation is essential for progress, long-term growth, and consumer welfare. As such, there is almost a universal consensus among economists that innovation must be not only protected but promoted. However, research remains unclear as regards the role competition plays in pursuing this goal. The relationship between competition and innovation is complex and ambiguous (Aghion et al., 2005; Shapiro, 2011). Discussions are thus still ongoing ...
Enzymatic treatment for age-related macular degeneration and excessive burn scars Ghent University
Next to the cataract treatment, which is currently being validated in the IOF Advanced project F2017/IOF–dvanced /089, we identified two novel clinical applications with a high market potential for the enzymatic treatment. One application (also in opthalmology) is age-related macular degeneration (AMD), a common cause of irreversible loss of sight for which at the current time no treatment is available. The second clinical application is ...
One for all, all for one? A research into the steps towards violent Islamist extremism: what it takes to make costly sacrifices. Ghent University
This research examines the process towards Violent Islamist Extremism and explores what it takes
to make costly sacrifices. We start from an integrated theoretical framework combining the
Significance Quest Theory (SQT) and the Devoted Actor Theory (DAT). According to both theories,
‘the need for personal significance’ is the dominant motivational force underlying the process
towards Violent Islamist Extremism. This ...
The role of entrepreneurs' temporal perspectives in the emergence of entrepreneurial opportunities Ghent University
Opportunities are at the very heart of entrepreneurship and are subject to a fierce debate on
whether they are made (created) or found (discovered). The goal of the proposed research is to
gain a profound theoretical understanding on the role of entrepreneurs’ temporal perspectives in
the emergence of entrepreneurial opportunities. Temporal perspectives can be understood as the
various ways in how individuals perceive ...
TransSIMS: Transition to Smart Industrial Production Systems in Industry 4.0 KU Leuven
Building new Industry 4.0 plants on a “greenfield” is currently hardly realistic for small and medium-sized enterprises (SMEs). Giving the long life-times of production facilities, the solution is to be found in transforming the existing machines and systems into interconnected smart machines and systems. For that, IoT (Internet of Things) technologies, which are universally applicable and easy to use, can be exploited to increase the overall ...
Food justice and citizen-driven governance of urban agriculture. Assessing the co-creative design of multi-stakeholder governance of urban agriculture initiatives. University of Antwerp
Recommender Systems for Personalized Applications KU Leuven
Users in different services are faced by huge amount of content, which are mostly irrelevant. Therefore, there should be recommender systems to filter more relevant contents. The model-based recommender systems try to learn users preferences and build user profiles based on their implicit and explicit interactions with the service. They use user profiles to show them more relevant content, but the highly relevant content is not the only goal ...
Systematic bio-inspired design: from concept to validated functionality KU Leuven
Millions of years of evolution have allowed organisms to produce innovative solutions for the same problems designers encounter every day. During bio-inspired design, the interesting working principles that make the biological solution work are extracted and transferred to the design problem. Previous research has shown that this results in more novel designs. Furthermore, since biologists have already been studying organisms for centuries, ...