Publications
The cumulus cell gene expression profile of oocytes with different nuclear maturity and potential for blastocyst formation. Vrije Universiteit Brussel
METHODS: Quantitative PCR analysis of Has2, Vcan, Sdc4, Alcam, Grem1, Ptgs1 and Ptgs2 in CC collected at regular ...
Deposition of the spermatozoon in the human oocyte at ICSI: impact on oocyte survival, fertilization and blastocyst formation Vrije Universiteit Brussel
To evaluate whether the deposition of the spermatozoon in the human oocyte at ICSI has any effect on oocyte survival, fertilization, blastocyst development and quality.
METHODS:
In a prospective study, including 78 ICSI cycles, sibling oocytes were injected with "no intention" (group A, standard ICSI, n = 393) or "intention" to deposit the spermatozoon under the cortex (group B, n = 354). Outcome ...
Reduced blastocyst formation in reduced culture volume Vrije Universiteit Brussel
PURPOSE: The aim of this prospective sibling oocyte study was to evaluate whether reduced culture volume improves blastocyst formation.
METHODS: Twenty-three patients with extended embryo culture until day 5 were selected for the study. After injection, 345 sibling oocytes were individually cultured in either 25 or 7 μl droplets of Origio cleavage medium under oil. On day 3 of development, embryos were transferred to droplets with the ...
Genetic control of bovine blastocyst formation Ghent University
Impact of cleavage-stage embryo biopsy in view of PGD on human blastocyst implantation: a prospective cohort of single embryo transfers. Vrije Universiteit Brussel
Regulatory microRNA Network Identification in Bovine Blastocyst Development KU Leuven Ghent University
Inhibition of transforming growth factor U+03B2 signaling promotes epiblast formation in mouse embryos Ghent University University of Antwerp
Effect of small molecule supplements during in vitro culture of mouse zygotes and parthenogenetic embryos on hypoblast formation and stem cell derivation Ghent University
Influence of ultra-low oxygen (2%) tension on in-vitro human embryo development Vrije Universiteit Brussel
STUDY QUESTION: Is a reduction in the oxygen tension from 5 to 2% during extended culture from Day 3 onwards beneficial for human blastocyst development in vitro?
SUMMARY ANSWER: A reduction in oxygen concentration from 5 to 2% O2 after Day 3 did not improve embryo development, quality and utilization rate.
WHAT IS KNOWN ALREADY: The human embryo leaves the fallopian tube to reach the uterine cavity around Day 3-4 ...