Projects
Immunoassay design of a fiber optic biosensor for medical and agro-food applications KU Leuven
Over the last decades, biosensors have emerged as innovative tools at the interface between advanced biotechnology and sensor technology. They have been used in multiple applications, ranging from agricultural industry and food safety to medical diagnosis and environmental monitoring, and they have drawn increasing commercial attention from the market. The ever increasing cost in the healthcare sector has driven the research towards ...
INNOVATIVE NUCLEIC ACID BASED STRATEGIES FOR FIBER OPTIC SURFACE PLASMON RESONANCE BIOSENSOR DESIGN KU Leuven
The diverse information embedded in the specific sequence of DNA molecules has been feeding our understanding and insights in disease heritage, spreading and evolution. Ultrasensitive detection of the DNA molecules themselves is crucial for the early-stage detection of several diseases, as it facilitates the minimization of actual disease burden. Gold standard technologies, such as the polymerase chain reaction (PCR), are mainly restricted to ...
Designing affinity-based nanoswitches on a fiber optic surface plasmon resonance biosensor for continuous biomarker monitoring KU Leuven
Throughout the last decades, biomarker monitoring has become standard practice in health care, biotechnology, environmental analysis, and food production among others, as it enables diagnosis, intervention, and quality control. However, this is currently performed via batch measurements, for which samples have to be obtained from the environment of interest, transported to well-equipped laboratories and pretreated, before measurements can be ...
Designing affinity-based nanoswitches on a fiber optic surface plasmon resonance biosensor for continuous biomarker monitoring. KU Leuven
From peroxidase to biosensor - immobilization of dye-decolorizing peroxidase on titania for phenol sensing. University of Antwerp
Biosensor functionality for cochlear implants KU Leuven
Cochlear implants (CI) are considered the most successful sensory prosthesis, providing a solution for severe to complete deafness. Despite widespread clinical success of CI, little is known on how to avoid cochlear damage and inflammation during surgical insertion. This is crucial to preserve residual hearing and facilitate re-implantation, which is expected 2-3 times for a congenitally deaf child during lifespan. In this project we will ...
Digital microfluidic lab-on-a-chip for biosensor technology and (bio)catalysis. KU Leuven
Development and application of an innovative FRET-based biosensor system in Candida albicans KU Leuven
Infections caused by Candida albicans are becoming harder to eradicate due to increasing resistance against the widely used antifungals. In addition to the increasing resistance, the population of immunocompromised people (e.g. the elderly, neonates, etc.), which are extremely susceptible, is expanding. Therefore, novel therapies have to be discovered to treat and prevent fungal infections if we do not want to lose the arm’s race between ...