Towards model-based feedback control of bioreactors for bone tissue engineering. Monitoring of cellular response in a defined bioreactor environmnent. KU Leuven
Despite the significant advances in tissue engineering (TE) research there is still a very limited number of regularly used clinical applications in this area. One of the reasons for this difficult transition is thelack of consistent product quality caused by inadequately controlled production systems. This thesis was performed within the scope of an interdisciplinary research program on bone TE which aims at developing and quantitatively ...