Projects
Translocation of black carbon from the mother to the fetus. Development of a new internal label-free biomarker of black carbon exposures and its link with the early life origin of health and disease concept. KU Leuven
Current ambient outdoor air pollution concentrations are responsible for 3.7 million premature deaths worldwide. The combustion-related particulate matter (PM) air pollution, indicated as black carbon (BC), increases cardiovascular morbidity and mortality, but also chronic respiratory diseases and lung cancer. Two hypotheses are used to explain these findings both from experimental as well as epidemiological studies. First, particles produce ...
INCALO: Internal Black Carbon Loading: validation of a novel biomarker Hasselt University
Cellular communication as target and biomarker in liver disease and toxicity: from basic research towards clinical application Vrije Universiteit Brussel
EV-TRACE: Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage Ghent University
Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage (EV-TRACE) A major challenge in cancer is to detect the disease early on and it locate organ of origin while stratifying patients to receive appropriate treatment to increase survival and quality of life. Most cancers that are detected early can only be cured by surgery; so without any systemic therapy. New, inexpensive and ...
Extracellular Vesicle Tracking using surface proteins and Resonance Assays to detect breast Cancer in Early stage (EV-TRACE) KU Leuven
Problem
Early detection reduces cancer-related deaths because time is a matter of life and death for a cancer victim. Diagnostic screening tests must be sensitive, specific, inexpensive, non-invasive and provide sufficient lead-time. Single markers typically lack sensitivity and specificity. Extracellular Vesicles (EV) in liquid biopsies hold promise in the non-invasive detection of cancer because their molecular content (proteins, ...
Cardiac biomarkers, two-dimensional Speckle Tracking and Tissue Doppler Imaging for objective assessment of mitral and aortic regurgitation in horses Ghent University
Cardiac valvular regurgitation is frequently found in sport horses, especially at the mitral and aortic valves. New tissue Doppler imaging, and biochemical blood examination for cardiac biomarkers will be used to quantify valvular regurgitation and to identify prognostic parameters.