Projects
Capture, dissemination and analysis of multiscale cell migration data for biological and clinical applications (MULTIMOT) Ghent University
Cell migration is the fundamental process in medically highly relevant topics, including morphogenesis, immune function, wound healing,and cancer metastasis, and the study of cell migration thus has a direct impact on major clinical applications, especially regarding personalized treatment and diagnosis. Over the last few years, cell migration research has benefited enormously from advances in methodology and instrumentation, allowing ...
Post harvest application of biological control organisms (BCOs) against fruit storage disease Research Institute for Agriculture, Fisheries and Food
In the control of storage diseases of apple and pear, several methods are available for the fruit grower. The available pre- and post-harvest treatments, however, all have their limitations. Biological control of storage diseases using biological control organisms (BCOs) provides a safer and more environmentally friendly alternative and opens perspectives for further integrated production. The ...
Structural and biological evaluation of Xylonucleic acids (XNA) as a potential tool for synthetic biology/oligonucleotide based therapeutic application. KU Leuven
Development, validation and clinical application of assas in order to perform blood concentration measurements of biological. KU Leuven
The introduction of biologics has heralded a new era for treatment of immune-mediated inflammatory diseases (IMIDs), including ankylosing spondylitis (AS), psoriasis and inflammatory bowel diseases (IBD). Although these agents show efficacy in many patients, a substantial proportion of patients fails to respond, loses response over time or develops potentially therapy-limiting adverse events. One possible mechanism explaining the failure of ...
Development and application of broadly applicable microscopy methods and probes for diffraction-unlimited fluctuation imaging of dynamic biological systems. KU Leuven
Fluorescence imaging has seen a tremendous evolution over the last decade with the advent of methods circumventing the optical diffraction barrier, which has classically limited the fineness with which samples can be resolved to about 200 nanometers. To date, however, imaging at high spatial resolution has become reality but it comes with a cost: superresolution imaging is performed at the expense of a significantly reduced time resolution, ...
New methodology for the calculation of local magnetic anisotropy effects in large polynuclear complexes of biological interest and single-molecule magnets: developments, implementation and application. KU Leuven
Compost application and the interaction between compost-and native soil fauna: nematodes as indicator of biological compost maturity and soil food web processes. Ghent University
Experiments will elucidate whether thoroughly characterized composts, differentiated based on their nematode communities, have different effects on soil properties and nematode assemblages. An ecometagenetics approach will distinguish between compost- and native assemblages and reveal if the nematodes in compost directly contribute to the nematode community in the soil vs. that observed effects are due to the overall stimulation of the soil ...
Form follows function: design, development and application of a new tool to assess how the 3D microstructure of biological tissues changes during mechanical loading KU Leuven
Biological tissues undergo physiological mechanical loading during their functioning in vivo. To properly respond to these mechanical signals, tissues have a highly complex microstructural organization. However, there is not yet sufficient knowledge about the link between their microstructural organization and their mechanical behaviour. Therefore, this PhD project aims to optimize a novel tool that allows to dynamically assess in 3D how the ...