Engineered phages and tailocins targeting Shiga toxin-producing Escherichia coli (STEC) Ghent University
Bacteriophages are viruses that infect bacteria. Their receptor-binding proteins (RBPs) specifically bind
bacterial outer cell structures. Tailocins are morphologically similar to head-less myovirus
bacteriophages. This project aims to turn well-characterized, safe phages and tailocins into highly
specific Shiga toxin-producing Escherichia coli (STEC) targeting compounds by swapping RBPs across
phages, followed by a ...