Modulation of bacterial adherence in infective endocarditis: impact of different conduit tissues used in right ventricular outflow tract valve replacement and bacterial surface molecules under shear stress. KU Leuven
Infective endocarditis (IE) is defined as an infection of the endocardial surface of the heart, which may include one or more heart valves, and is lethal if not aggressively treated. IE can have numerous causes, but is a major clinical problem in patients after transcatheter or surgical valve replacement. Treatment of IE is challenged by the high propensity of bacteria, in particular Staphylococcus aureus, to induce inflammatory and ...