Projects
Ventricular-arterial coupling disease as pathogenic link between subclinical heart failure and arterial stiffening. KU Leuven
Current heart failure (HF) guidelines place special emphasis on the early detection of people with subclinical left ventricular (LV) remodeling and dysfunction. To better understand the mechanism of LV remodeling related to cardiovascular risk factors such as hypertension and diabetes, it is important to evaluate LV function in relation to changes in loading, i.e. preload and afterload. For instance, arterial stiffening increases the vascular ...
Research network for Arterial Calcification University of Antwerp
Modeling non-invasive arterial tissue characterization using ultrsound Ghent University
In this PhD-project, we aim to investigate the potential of ultrasound to quantify the mechanical properties of healthy and pathological arterial tissue based on computational models. First, we will acquire more insight into the interaction of acoustic waves with the tissue at microstructural level. Secondly, clinically applicable ultrasound modalities for arterial tissue characterization will be simulated and validated.
Personalized diagnosis and treatment of aortic aneurysms through in-depth microstructural tissue analysis KU Leuven
Cardiovascular diseases are the leading cause of death worldwide. In Belgium, at least 60 000 people suffer from an aortic aneurysm, a permanent dilatation of the aorta caused by weakening in the aortic wall. The most feared complication is aortic dissection or rupture, associated with mortality rates up to 95%. Despite these alarming numbers, the diagnosis and treatment of aortic aneurysms have hardly evolved over the last 20 years.
...BMP signalling in vascular biology and disease signalling University of Antwerp
Development and validation of a non-invasive, non-contact, optical measurement method for detection of local pulse wave velocity in the common carotid artery. University of Antwerp
Phenotyping atherosclerosis: morphological and functional research of the intima and media layer of the carotid and femoral artery Ghent University
The principal aims of this research project are to map the variation of arterial stiffness and thickness of the intima-media complex (IMT) along the carotid and femoral artery in a representative sample of the general population and to formulate guidelines for the standardisation of measurement of IMT and local stiffness of a blood vessel.