Steering tumors towards a ferroptosis-mediated immunogenic death by exploiting vulnerabilities in lipid metabolism KU Leuven
While precision therapies are revolutionizing the way in which we treat cancer, a growing body of evidence indicates that the long-term success of current treatments heavily relies on the induction of efficient cell death, along with the elicitation of tumor antigen-directed antitumor immunity. Among the key factors determining this response is the mechanism of cell death induced by therapeutic interventions. Whereas classical apoptosis often ...