Projects
Study of the interaction between external triggers and the airway barrier in asthma and study of the role of gradual introduction of food allergens for induction and/of maintenance of tolerance in food allergy KU Leuven
In the next 5 years I) I will focus on airway inflammation in (non-allergic) asthma. While the underlying mechanisms of the allergic asthma phenotype are well identified, the pathogenesis of non-allergic asthma phenotypes remains largely unexplored. We hypothesize that triggering of epithelial cells (EC) and subsequent activation of innate lymphoid cells (ILCs) are responsible for the pathophysiology of these non-allergic asthma phenotypes by ...
Neuro-immune mechanisms of visceral and respiratory hypersensitivity KU Leuven
Characterization and role of innate lymphoid cell subtypes in non-allergic asthma KU Leuven
Physiology and pathophysiology of sensory cells: from the physics to the clinics. KU Leuven
The survival of living organisms relies critically on their abilities to sense and react properly to ever changing environmental conditions, and understanding the mechanisms underlying the functions of sensory systems is key for the development of strategies to improve human health. This research plan aims at investigating the mechanisms of sensory processing, using a variety of theoretical and experimental approaches, at levels from ...