Study of the molecular mechanisms regulating the activity and expression of the de-ubiquitinase protein DUBA in innate immune signaling. Ghent University
The research project wants to contribute to the study of negative regulators in the innate immune system. More precisely, we want to study the de-ubiquitinase DUBA, a negative regulator in the signaling pathway important for the production of type I interferons and antiviral responses. We want to gain a thorough knowledge of the molecular and biochemical mechanisms regulating the function of DUBA.