Translocase dynamics of the Type 3 secretion system of enteropathogenic E. coli KU Leuven
The Type III protein secretion system (T3SS) mainly found in gram negative bacteria specializes in delivering bacterial toxins into the cytoplasm of host eukaryotic cells through the injectisome. Once secreted, effectors interfere with host signaling and modulate cellular processes, leading to host cell death. It is responsible for several severe diseases, like the plague (Yersinia pestis), typhoid fever (Salmonella enterica) and infantile ...