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PGA(1)-induced apoptosis involves specific activation of H-Ras and N-Ras in cellular endomembranes KU Leuven
The cyclopentenone prostaglandin A1 (PGA1) is an inducer of cell death in cancer cells. However, the mechanism that initiates this cytotoxic response remains elusive. Here we report that PGA1 triggers apoptosis by a process that entails the specific activation of H- and N-Ras isoforms, leading to caspase activation. Cells without H- and N-Ras did not undergo apoptosis upon PGA1 treatment; in these cells, the cellular demise was rescued by ...
Understanding the mechanical strength and dynamic structural changes of wood-based products using X-ray computed tomography Ghent University
The mechanical strength of wood-based products (WBP) is determined by the anatomical structure of wood, including the specificities of earlywood (EW) and latewood (LW), and the bonding interphase between wood and adhesive. In this study, two-layered specimens were manufactured according to three possible assembling strategies in terms of the anatomical structure of wood. Wood micro-structure and phenol formaldehyde (PF) adhesive distribution ...
HEXITEC 2 × 2 tiled hard X-ray spectroscopic imaging detector system Ghent University
HEXITEC is a spectroscopic imaging X-ray detector technology developed at the STFC Rutherford Appleton Laboratory for X-ray and gamma-ray spectroscopic imaging applications. Each module has 80 x 80 pixels on a 250 mu m pixel pitch, and has been implemented successfully in a number of applications. This paper presents the HEXITEC 2 x 2 detector system, a tiled array of 4 HEXITEC modules read out simultaneously, which provides an active area of 16 ...
X-ray absorption as an alternative method to determine the exhausting degree of activated carbon layers in water treatment system for medical services Hasselt University
Analytical methods based on X-Ray radiation proved to be reliable and sensitive techniques to study activated carbons (ACs). An X-Ray absorption analysis based on digital radiographic images (XRA) is applied for the determination of the exhaustion degree of granular activated carbon (GAC) used in a water purification system for hemodialysis. XRA-method demonstrated the possibility to determine the exhaustion degree at different layers of the GAC ...
Realizing simultaneous X-ray Imaging and dosimetry using phosphor-based detectors with high memory stability and convenient readout process Ghent University
Detection of gold nano-particles in atherosclerotic plaque using hyperspectral X-ray imaging Ghent University
The influence of X-ray resonant Raman scattering effects on the detection of CuTSPc thin-films deposited on gold electrodes Ghent University University of Antwerp
New imaging modalities in high resolution X-ray tomography Ghent University
For more than 100 years, X-rays are used in medical diagnostics, materials science and many other research domains for the possibility they offer to look through objects. Since the 1970s, Computed Tomography or CT allows for acquiring a full 3D representation of an object or a patient. In the 1980s, technological advances led to the development of high resolution X-ray CT or µCT. Using this technique, objects can be investigated with a spatial ...