The study of HIV-1 uncoating by super-resolution imaging of fluorescently labeled capsid. KU Leuven
Single-virus fluorescence experiments provide a powerful tool to study the HIV-1 replication cycle, which is characterised by fast and transient events, essential virus-host interactions and an overall heterogeneous nature. Specific labelling of a viral protein of interest without inhibiting viral infectivity allows to monitor individual steps of the replication cycle in space and time. In this thesis, we aimed to investigate the fate of both ...