Dengue virus infection of endothelial cells: Pathogenesis and antiviral potential of glycosaminoglycan targeting KU Leuven
Dengue viruses (DENV) are single-stranded positive-sense RNA viruses that belong to the family of the Flaviviridae, together with other important human pathogens (e.g. yellow fever virus and West Nile virus). Dengue is currently considered to be the most important arthropod-borne vial disease in humans. Four genetically distinct, but serologically related serotypes (DENV 1-4) are transmitted to humans by mosquitoes of the ...